Exploring the Immunogenicity of Noncanonical HLA-I Tumor Ligands Identified through Proteogenomics

PURPOSE: Tumor antigens are central to antitumor immunity. Recent evidence suggests that peptides from noncanonical (nonC) aberrantly translated proteins can be presented on HLA-I by tumor cells. Here, we investigated the immunogenicity of nonC tumor HLA-I ligands (nonC-TL) to better understand thei...

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Detalles Bibliográficos
Autores principales: Lozano-Rabella, Maria, Garcia-Garijo, Andrea, Palomero, Jara, Yuste-Estevanez, Anna, Erhard, Florian, Farriol-Duran, Roc, Martín-Liberal, Juan, Ochoa-de-Olza, Maria, Matos, Ignacio, Gartner, Jared J., Ghosh, Michael, Canals, Francesc, Vidal, August, Piulats, Josep Maria, Matías-Guiu, Xavier, Brana, Irene, Muñoz-Couselo, Eva, Garralda, Elena, Schlosser, Andreas, Gros, Alena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261919/
https://www.ncbi.nlm.nih.gov/pubmed/36749875
http://dx.doi.org/10.1158/1078-0432.CCR-22-3298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261919/
https://www.ncbi.nlm.nih.gov/pubmed/36749875
http://dx.doi.org/10.1158/1078-0432.CCR-22-3298

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