Decrypting the potency of anti-cancer therapeutics by using mass spectrometry to quantify post-translational modifications

In a recent issue of Science, Zecha et al.(1) present decryptM, an approach aimed at defining the mechanisms of action of anti-cancer therapeutics through systems-level analysis of protein post-translational modifications (PTMs). By using a broad range of concentrations, decryptM generates drug resp...

Descripción completa

Detalles Bibliográficos
Autores principales: Herbst, Sophie A., White, Forest M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261922/
https://www.ncbi.nlm.nih.gov/pubmed/37323574
http://dx.doi.org/10.1016/j.crmeth.2023.100483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261922/
https://www.ncbi.nlm.nih.gov/pubmed/37323574
http://dx.doi.org/10.1016/j.crmeth.2023.100483

Ejemplares similares