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Decrypting the potency of anti-cancer therapeutics by using mass spectrometry to quantify post-translational modifications
In a recent issue of Science, Zecha et al.(1) present decryptM, an approach aimed at defining the mechanisms of action of anti-cancer therapeutics through systems-level analysis of protein post-translational modifications (PTMs). By using a broad range of concentrations, decryptM generates drug resp...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261922/ https://www.ncbi.nlm.nih.gov/pubmed/37323574 http://dx.doi.org/10.1016/j.crmeth.2023.100483 |