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Reassessment of miRNA variant (isomiRs) composition by small RNA sequencing

IsomiRs, sequence variants of mature microRNAs, are usually detected and quantified using high-throughput sequencing. Many examples of their biological relevance have been reported, but sequencing artifacts identified as artificial variants might bias biological inference and therefore need to be id...

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Detalles Bibliográficos
Autores principales: Gómez-Martín, Cristina, Aparicio-Puerta, Ernesto, van Eijndhoven, Monique A.J., Medina, José M., Hackenberg, Michael, Pegtel, D. Michiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261927/
https://www.ncbi.nlm.nih.gov/pubmed/37323569
http://dx.doi.org/10.1016/j.crmeth.2023.100480