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Spinal cord vascular degeneration impairs duloxetine penetration

INTRODUCTION: Chronic pain is a prevalent physically debilitating health-related morbidity. Frontline analgesics are inadequate, providing only partial pain relief in only a proportion of the patient cohort. Here, we explore whether alterations in spinal cord vascular perfusion are a factor in reduc...

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Detalles Bibliográficos
Autores principales: Da Vitoria Lobo, M. E, Madden, R, Liddell, S, Hirashima, M, Hulse, R. P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262048/
https://www.ncbi.nlm.nih.gov/pubmed/37325676
http://dx.doi.org/10.3389/fpain.2023.1190440