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Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice

Acute respiratory distress syndrome (ARDS) is a life-threatening disorder with a high rate of mortality. Complement activation in ARDS initiates a robust inflammatory reaction that can cause progressive endothelial injury in the lung. Here, we tested whether inhibition of the lectin pathway of compl...

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Detalles Bibliográficos
Autores principales: Ali, Youssif M., Lynch, Nicholas J., Shaaban, Ahmed A., Rizk, Dina E., Abdel-Rahman, Shaymaa H., Khatri, Priyanka, Yabuki, Munehisa, Yaseen, Sadam, Dudler, Thomas, Demopulos, Gregory, Schwaeble, Wilhelm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262210/
https://www.ncbi.nlm.nih.gov/pubmed/37325666
http://dx.doi.org/10.3389/fimmu.2023.1192767