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5-Chloro-8-nitro-1-naphthoyl (NNap): A Selective Protective Group for Amines and Amino Acids

[Image: see text] The synthesis of 5-chloro-8-nitro-1-naphthoyl chloride and its use as a protective group for amines is described. Protection is carried out with an auxiliary amine or under mild Schotten-Baumann conditions in high yield (>86%), while deprotection can be achieved easily under gen...

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Detalles Bibliográficos
Autores principales: Habib, Asmaa, Garrido-González, José J., Sánchez-Santos, Estela, del Teso, Irene Boya, Sanz, Francisca, Alcázar, Victoria, Fuentes de Arriba, Ángel L., Morán, Joaquín R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262267/
https://www.ncbi.nlm.nih.gov/pubmed/37232572
http://dx.doi.org/10.1021/acs.orglett.3c01334