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DNA mismatch repair in cancer immunotherapy

Tumors defective in DNA mismatch repair (dMMR) exhibit microsatellite instability (MSI). Currently, patients with dMMR tumors are benefitted from anti-PD-1/PDL1-based immune checkpoint inhibitor (ICI) therapy. Over the past several years, great progress has been made in understanding the mechanisms...

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Detalles Bibliográficos
Autores principales: Guan, Junhong, Li, Guo-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262306/
https://www.ncbi.nlm.nih.gov/pubmed/37325548
http://dx.doi.org/10.1093/narcan/zcad031