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Using modified intention-to-treat as a principal stratum estimator for failure to initiate treatment
BACKGROUND: A common intercurrent event affecting many trials is when some participants do not begin their assigned treatment. For example, in a double-blind drug trial, some participants may not receive any dose of study medication. Many trials use a ‘modified intention-to-treat’ approach, whereby...
Autores principales: | Kahan, Brennan C, White, Ian R, Edwards, Mark, Harhay, Michael O |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262320/ https://www.ncbi.nlm.nih.gov/pubmed/36916466 http://dx.doi.org/10.1177/17407745231160074 |
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