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Comparison of the pathological response to 2 or 4 cycles of neoadjuvant CAPOX in II/III rectal cancer patients with low/intermediate risks: study protocol for a prospective, non-inferior, randomized control trial (COPEC trial)

BACKGROUND: For patients with low- and intermediate-risk stage II/III rectal cancer, current studies have reached a consensus that preoperative radiotherapy may be dispensed with, and neoadjuvant chemotherapy (NCT) alone might achieve an accepted local control. Our previous phase II study has eviden...

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Detalles Bibliográficos
Autores principales: Shen, Yu, Shi, Wanyue, Huang, Cui, Gong, Xiaoling, Wei, Mingtian, Meng, Wenjian, Deng, Xiangbing, Wang, Ziqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262432/
https://www.ncbi.nlm.nih.gov/pubmed/37312165
http://dx.doi.org/10.1186/s13063-023-07405-x