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Evolution of carbapenem resistance in klebsiella pneumoniae and escherichia coli carrying bla(NDM−1) gene: imipenem exposure results in sustained resistance memory of strains in vitro

BACKGROUND: Antibiotics exert an outstanding selective pressure on bacteria, forcing their chromosomal gene mutations and drug resistance genes to spread. The objective of this study is to evaluate the expression of the New Delhi Metallo-β-Lactamase-1 gene (bla(NDM−1)) in the clinical isolate (Klebs...

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Detalles Bibliográficos
Autores principales: Zhao, Qiong, Sha, Longhua, Wu, Zhaomeng, Meng, Lixue, Yang, Feixiang, Wu, Lingling, Yu, Chunfang, Zhang, Hua, Yu, Jingdan, Jin, Zhixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262507/
https://www.ncbi.nlm.nih.gov/pubmed/37308958
http://dx.doi.org/10.1186/s12941-023-00598-8