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Evolution of carbapenem resistance in klebsiella pneumoniae and escherichia coli carrying bla(NDM−1) gene: imipenem exposure results in sustained resistance memory of strains in vitro
BACKGROUND: Antibiotics exert an outstanding selective pressure on bacteria, forcing their chromosomal gene mutations and drug resistance genes to spread. The objective of this study is to evaluate the expression of the New Delhi Metallo-β-Lactamase-1 gene (bla(NDM−1)) in the clinical isolate (Klebs...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262507/ https://www.ncbi.nlm.nih.gov/pubmed/37308958 http://dx.doi.org/10.1186/s12941-023-00598-8 |