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ABCA1 transporter promotes the motility of human melanoma cells by modulating their plasma membrane organization

BACKGROUND: Melanoma is one of the most aggressive and deadliest skin tumor. Cholesterol content in melanoma cells is elevated, and a portion of it accumulates into lipid rafts. Therefore, the plasma membrane cholesterol and its lateral organization might be directly linked with tumor development. A...

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Detalles Bibliográficos
Autores principales: Wu, Ambroise, Mazurkiewicz, Ewa, Donizy, Piotr, Kotowski, Krzysztof, Pieniazek, Małgorzata, Mazur, Antonina J., Czogalla, Aleksander, Trombik, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262546/
https://www.ncbi.nlm.nih.gov/pubmed/37312227
http://dx.doi.org/10.1186/s40659-023-00443-4