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Inhalable CAR-T cell-derived exosomes as paclitaxel carriers for treating lung cancer

BACKGROUND: Non-small cell lung cancer (NSCLC) is a worldwide health threat with high annual morbidity and mortality. Chemotherapeutic drugs such as paclitaxel (PTX) have been widely applied clinically. However, systemic toxicity due to the non-specific circulation of PTX often leads to multi-organ...

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Detalles Bibliográficos
Autores principales: Zheng, Wei, Zhu, Tianchuan, Tang, Lantian, Li, Zhijian, Jiang, Guanmin, Huang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262566/
https://www.ncbi.nlm.nih.gov/pubmed/37308954
http://dx.doi.org/10.1186/s12967-023-04206-3