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Analysis of PEG-lipid anchor length on lipid nanoparticle pharmacokinetics and activity in a mouse model of traumatic brain injury

Traumatic brain injury (TBI) affects millions of people worldwide, yet there are currently no therapeutics that address the long-term impairments that develop in a large portion of survivors. Lipid nanoparticles (LNPs) are a promising therapeutic strategy that may address the molecular basis of TBI...

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Detalles Bibliográficos
Autores principales: Waggoner, Lauren E., Miyasaki, Katelyn F., Kwon, Ester J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262813/
https://www.ncbi.nlm.nih.gov/pubmed/36987922
http://dx.doi.org/10.1039/d2bm01846b