Characterization of HZ0412a, a novel potent humanized anti-IL-6 receptor antibody that blocks IL-6R binding to gp130

Dysregulated elevation of interleukin-6 (IL-6) signaling is implicated in the pathogenesis of multiple pathophysiological states, and the functional neutralization of the IL-6 pathway with monoclonal antibodies has been proven an effective therapeutic method in treating various diseases with abnorma...

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Detalles Bibliográficos
Autores principales: Han, Jianzhong, Liu, Xiaolei, Xu, Yue, Wang, Qian, Li, Li, Du, Kehe, Li, Chenchen, Liu, Hongjun, Chen, Yu, Huang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262838/
https://www.ncbi.nlm.nih.gov/pubmed/37324549
http://dx.doi.org/10.1093/abt/tbad008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262838/
https://www.ncbi.nlm.nih.gov/pubmed/37324549
http://dx.doi.org/10.1093/abt/tbad008

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