Generation of two induced pluripotent stem cell lines with heterozygous and homozygous amyotrophic lateral sclerosis-causing mutation P525L (c.1574C > T) in FUS gene

Mutations in the FUS (fused in sarcoma) gene are implicated in the neurodegenerative disease amyotrophic lateral sclerosis (ALS). However, the pathophysiology underlying these mutations remains elusive. In this study, we created two induced pluripotent stem cell (iPSC) lines through genetic modifica...

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Detalles Bibliográficos
Autores principales: Akter, Masuma, Cui, Haochen, Hosain, Md Abir, Ding, Baojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262954/
https://www.ncbi.nlm.nih.gov/pubmed/37116345
http://dx.doi.org/10.1016/j.scr.2023.103103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262954/
https://www.ncbi.nlm.nih.gov/pubmed/37116345
http://dx.doi.org/10.1016/j.scr.2023.103103

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