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Toll-like Receptor 4 Is Upregulated in Parkinson’s Disease Patients and Co-Localizes with pSer129αSyn: A Possible Link with the Pathology

Growing evidence suggests a crucial role of neuroinflammation in the pathophysiology of Parkinson’s disease (PD). Neuroinflammation is linked to the accumulation and aggregation of a-synuclein (αSyn), the primary pathological hallmark of PD. Toll-like receptors 4 (TLR4) can have implications in the...

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Detalles Bibliográficos
Autores principales: Conte, Carmela, Ingrassia, Angela, Breve, John, Bol, John J., Timmermans-Huisman, Evelien, van Dam, Anne-Marie, Beccari, Tommaso, van de Berg, Wilma D. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10263232/
https://www.ncbi.nlm.nih.gov/pubmed/37408202
http://dx.doi.org/10.3390/cells12101368