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Regulation of EBNA1 protein stability and DNA replication activity by PLOD1 lysine hydroxylase

Epstein-Barr virus (EBV) is a ubiquitous human γ-herpesvirus that is causally associated with various malignancies and autoimmune disease. Epstein-Barr Nuclear Antigen 1 (EBNA1) is the viral-encoded DNA binding protein required for viral episome maintenance and DNA replication during latent infectio...

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Detalles Bibliográficos
Autores principales: Dheekollu, Jayaraju, Wiedmer, Andreas, Soldan, Samantha S., Castro- Muñoz, Leonardo Josué, Chen, Christopher, Tang, Hsin-Yao, Speicher, David W., Lieberman, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10263308/
https://www.ncbi.nlm.nih.gov/pubmed/37262099
http://dx.doi.org/10.1371/journal.ppat.1010478