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Macrophage inhibitory cytokine-1 aggravates diet-induced gallstone formation via increased ABCG5/ABCG8 expression

Macrophage inhibitory cytokine 1 (MIC-1), which is overproduced in various human cancers and associated with cachexia, acts on the hypothalamus to suppress appetite and reduce body weight. We investigated the mechanisms through which MIC-1 affects bile acid metabolism and gallstone formation, which...

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Detalles Bibliográficos
Autores principales: Kim, Min Hee, Lee, Eun-Ji, Kim, Su-Jeong, Jung, Yun-Jae, Park, Woo-Jae, Park, Inkeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10263326/
https://www.ncbi.nlm.nih.gov/pubmed/37310967
http://dx.doi.org/10.1371/journal.pone.0287146