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The Dantu blood group prevents parasite growth in vivo: Evidence from a controlled human malaria infection study

BACKGROUND: The long co-evolution of Homo sapiens and Plasmodium falciparum has resulted in the selection of numerous human genetic variants that confer an advantage against severe malaria and death. One such variant is the Dantu blood group antigen, which is associated with 74% protection against s...

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Detalles Bibliográficos
Autores principales: Kariuki, Silvia N, Macharia, Alexander W, Makale, Johnstone, Nyamu, Wilfred, Hoffman, Stephen L, Kapulu, Melissa C, Bejon, Philip, Rayner, Julian C, Williams, Thomas N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264070/
https://www.ncbi.nlm.nih.gov/pubmed/37310872
http://dx.doi.org/10.7554/eLife.83874