Identification of patient-specific CD4(+) and CD8(+) T cell neoantigens through HLA-unbiased genetic screens

Cancer neoantigens that arise from tumor mutations are drivers of tumor-specific T cell responses, but identification of T cell-recognized neoantigens in individual patients is challenging. Previous methods have restricted antigen discovery to selected HLA alleles, thereby limiting the breadth of ne...

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Detalles Bibliográficos
Autores principales: Cattaneo, Chiara M., Battaglia, Thomas, Urbanus, Jos, Moravec, Ziva, Voogd, Rhianne, de Groot, Rosa, Hartemink, Koen J., Haanen, John B. A. G., Voest, Emile E., Schumacher, Ton N., Scheper, Wouter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264241/
https://www.ncbi.nlm.nih.gov/pubmed/36593398
http://dx.doi.org/10.1038/s41587-022-01547-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264241/
https://www.ncbi.nlm.nih.gov/pubmed/36593398
http://dx.doi.org/10.1038/s41587-022-01547-0

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