Single-nucleus multi-omics of human stem cell-derived islets identifies deficiencies in lineage specification

Insulin-producing β cells created from human pluripotent stem cells have potential as a therapy for insulin-dependent diabetes, but human pluripotent stem cell-derived islets (SC-islets) still differ from their in vivo counterparts. To better understand the state of cell types within SC-islets and i...

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Detalles Bibliográficos
Autores principales: Augsornworawat, Punn, Hogrebe, Nathaniel J., Ishahak, Matthew, Schmidt, Mason D., Marquez, Erica, Maestas, Marlie M., Veronese-Paniagua, Daniel A., Gale, Sarah E., Miller, Julia R., Velazco-Cruz, Leonardo, Millman, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264244/
https://www.ncbi.nlm.nih.gov/pubmed/37188763
http://dx.doi.org/10.1038/s41556-023-01150-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264244/
https://www.ncbi.nlm.nih.gov/pubmed/37188763
http://dx.doi.org/10.1038/s41556-023-01150-8

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