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A randomised controlled trial of long NY-ESO-1 peptide-pulsed autologous dendritic cells with or without alpha-galactosylceramide in high-risk melanoma

AIM: We have previously reported that polyfunctional T cell responses can be induced to the cancer testis antigen NY-ESO-1 in melanoma patients injected with mature autologous monocyte-derived dendritic cells (DCs) loaded with long NY-ESO-1-derived peptides together with α-galactosylceramide (α-GalC...

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Detalles Bibliográficos
Autores principales: Dasyam, Nathaniel, Sharples, Katrina J., Barrow, Catherine, Huang, Ying, Bauer, Evelyn, Mester, Brigitta, Wood, Catherine E., Authier-Hall, Astrid, Dzhelali, Marina, Ostapowicz, Tess, Kumar, Rajiv, Lowe, Jessica, Maxwell, Alice, Burn, Olivia K., Williams, Geoffrey M., Carley, Sarah E., Caygill, Graham, Jones, Jeremy, Chan, Susanna T. S., Hinder, Victoria A., Macapagal, Jerome, McCusker, Monica, Weinkove, Robert, Brimble, Margaret A., Painter, Gavin F., Findlay, Michael P., Dunbar, P. Rod, Gasser, Olivier, Hermans, Ian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264280/
https://www.ncbi.nlm.nih.gov/pubmed/36881133
http://dx.doi.org/10.1007/s00262-023-03400-y