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Topical Isotretinoin (TMB-001) Treatment for 12 Weeks Did Not Result in Clinically Relevant Laboratory Abnormalities in Participants with Congenital Ichthyosis in the Phase 2b CONTROL Study

INTRODUCTION: Treatment with oral retinoids can be effective in patients with congenital ichthyosis (CI) but may be associated with clinically significant laboratory changes. In this Phase 2b CONTROL study analysis, we characterize the effects of TMB-001, a novel topical isotretinoin formulation, on...

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Detalles Bibliográficos
Autores principales: Marathe, Kalyani, Teng, Joyce M. C., Guenthner, Scott, Bunick, Christopher G., Kempers, Steven, Eads, Kimmie, Castelo-Soccio, Leslie, Mendelsohn, Alan M., Raiz, Jessica, Murrell, Dédée F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264299/
https://www.ncbi.nlm.nih.gov/pubmed/37170057
http://dx.doi.org/10.1007/s13555-023-00923-1