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Leaky Gut Plays a Critical Role in the Pathophysiology of Autism in Mice by Activating the Lipopolysaccharide-Mediated Toll-Like Receptor 4–Myeloid Differentiation Factor 88–Nuclear Factor Kappa B Signaling Pathway

Increased intestinal barrier permeability, leaky gut, has been reported in patients with autism. However, its contribution to the development of autism has not been determined. We selected dextran sulfate sodium (DSS) to disrupt and metformin to repair the intestinal barrier in BTBR T(+)tf/J autisti...

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Detalles Bibliográficos
Autores principales: Li, Fang, Ke, Haoran, Wang, Siqi, Mao, Wei, Fu, Cexiong, Chen, Xi, Fu, Qingqing, Qin, Xiaori, Huang, Yonghua, Li, Bidan, Li, Shibing, Xing, Jingying, Wang, Minhui, Deng, Wenlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264341/
https://www.ncbi.nlm.nih.gov/pubmed/36528850
http://dx.doi.org/10.1007/s12264-022-00993-9