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Targeting CDK1 in cancer: mechanisms and implications

Cyclin dependent kinases (CDKs) are serine/threonine kinases that are proposed as promising candidate targets for cancer treatment. These proteins complexed with cyclins play a critical role in cell cycle progression. Most CDKs demonstrate substantially higher expression in cancer tissues compared w...

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Detalles Bibliográficos
Autores principales: Wang, Qiushi, Bode, Ann M., Zhang, Tianshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264400/
https://www.ncbi.nlm.nih.gov/pubmed/37311884
http://dx.doi.org/10.1038/s41698-023-00407-7