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USP8 positively regulates hepatocellular carcinoma tumorigenesis and confers ferroptosis resistance through β-catenin stabilization

Hepatocellular carcinoma (HCC) is the most common type of primary hepatic carcinoma, which is a growing public health problem worldwide. One of the main genetic alterations in HCC is the deregulated Wnt/β-catenin signaling, activation of β-catenin is associated with the progression of HCC. In the pr...

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Detalles Bibliográficos
Autores principales: Tang, Jianing, Long, Guo, Xiao, Liang, Zhou, Ledu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264414/
https://www.ncbi.nlm.nih.gov/pubmed/37311739
http://dx.doi.org/10.1038/s41419-023-05747-7