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Temperature-triggered in situ forming lipid mesophase gel for local treatment of ulcerative colitis

Ulcerative colitis is a chronic inflammatory bowel disease that strongly affects patient quality of life. Side effects of current therapies necessitate new treatment strategies that maximise the drug concentration at the site of inflammation, while minimizing systemic exposure. Capitalizing on the b...

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Detalles Bibliográficos
Autores principales: Carone, Marianna, Spalinger, Marianne R., Gaultney, Robert A., Mezzenga, Raffaele, Hlavačková, Kristýna, Mookhoek, Aart, Krebs, Philippe, Rogler, Gerhard, Luciani, Paola, Aleandri, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264425/
https://www.ncbi.nlm.nih.gov/pubmed/37311749
http://dx.doi.org/10.1038/s41467-023-39013-3