Immune checkpoint inhibition combined with targeted therapy using a novel virus-like drug conjugate induces complete responses in a murine model of local and distant tumors

Metastases remain the leading cause of cancer-related death worldwide. Therefore, improving the treatment efficacy against such tumors is essential to enhance patient survival. AU-011 (belzupacap sarotalocan) is a new virus-like drug conjugate which is currently in clinical development for the treat...

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Detalles Bibliográficos
Autores principales: Huis in ‘t Veld, Ruben V., Ma, Sen, Kines, Rhonda C., Savinainen, Anneli, Rich, Cadmus, Ossendorp, Ferry, Jager, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264500/
https://www.ncbi.nlm.nih.gov/pubmed/36997666
http://dx.doi.org/10.1007/s00262-023-03425-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264500/
https://www.ncbi.nlm.nih.gov/pubmed/36997666
http://dx.doi.org/10.1007/s00262-023-03425-3

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