How Azide Ion/Hydrazoic Acid Passes Through Biological Membranes: An Experimental and Computational Study

Hydrazoic acid (HN(3)) and its deprotonated form azide ion (N(3)(−)) (AHA) are toxic because they inhibit the cytochrome c oxidase complex IV (CoX IV) embedded in the inner mitochondrial membrane that forms part of the enzyme complexes involved in cellular respiration. Critical to its toxicity is th...

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Detalles Bibliográficos
Autores principales: Hartl, Simona Lojevec, Žakelj, Simon, Dolenc, Marija Sollner, Smrkolj, Vladimir, Mavri, Janez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264542/
https://www.ncbi.nlm.nih.gov/pubmed/37289420
http://dx.doi.org/10.1007/s10930-023-10127-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264542/
https://www.ncbi.nlm.nih.gov/pubmed/37289420
http://dx.doi.org/10.1007/s10930-023-10127-3

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