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How Azide Ion/Hydrazoic Acid Passes Through Biological Membranes: An Experimental and Computational Study
Hydrazoic acid (HN(3)) and its deprotonated form azide ion (N(3)(−)) (AHA) are toxic because they inhibit the cytochrome c oxidase complex IV (CoX IV) embedded in the inner mitochondrial membrane that forms part of the enzyme complexes involved in cellular respiration. Critical to its toxicity is th...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264542/ https://www.ncbi.nlm.nih.gov/pubmed/37289420 http://dx.doi.org/10.1007/s10930-023-10127-3 |