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CREB5 hypermethylation involved in the ganglioside GM1 therapy of Parkinson’s disease

INTRODUCTION: The treatment with monosialotetrahexosylganglioside (GM1) improves the symptoms of Parkinson’s disease (PD). The alteration of DNA methylation in the blood was examined to investigate epigenetic modification by GM1 treatment. METHODS: After a 28-day continuous intravenous infusion of G...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Tong, Shanshan, Wang, Mengdi, Zou, Junjie, Wang, Nan, Sun, Fengjiao, Zhou, Xiaosheng, Chen, Jinbo, Wang, Hongcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264581/
https://www.ncbi.nlm.nih.gov/pubmed/37323142
http://dx.doi.org/10.3389/fnagi.2023.1122647