Investigating cell-specific effects of FMRP deficiency on spiny projection neurons in a mouse model of Fragile X syndrome

INTRODUCTION: Fragile X syndrome (FXS), resulting from a mutation in the Fmr1 gene, is the most common monogenic cause of autism and inherited intellectual disability. Fmr1 encodes the Fragile X Messenger Ribonucleoprotein (FMRP), and its absence leads to cognitive, emotional, and social deficits co...

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Detalles Bibliográficos
Autores principales: Giua, Gabriele, Lassalle, Olivier, Makrini-Maleville, Leila, Valjent, Emmanuel, Chavis, Pascale, Manzoni, Olivier J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264852/
https://www.ncbi.nlm.nih.gov/pubmed/37323585
http://dx.doi.org/10.3389/fncel.2023.1146647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264852/
https://www.ncbi.nlm.nih.gov/pubmed/37323585
http://dx.doi.org/10.3389/fncel.2023.1146647

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