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METTL3 Mediates Epithelial–Mesenchymal Transition by Modulating FOXO1 mRNA N(6)‐Methyladenosine‐Dependent YTHDF2 Binding: A Novel Mechanism of Radiation‐Induced Lung Injury

The biological roles of epithelial–mesenchymal transition (EMT) in the pathogenesis of radiation‐induced lung injury (RILI) have been widely demonstrated, but the mechanisms involved have been incompletely elucidated. N(6)‐methyladenosine (m(6)A) modification, the most abundant reversible methylatio...

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Detalles Bibliográficos
Autores principales: Feng, Yang, Yuan, Ping, Guo, Hongjuan, Gu, Liming, Yang, Zhao, Wang, Jian, Zhu, Wei, Zhang, Qi, Cao, Jianping, Wang, Lili, Jiao, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265050/
https://www.ncbi.nlm.nih.gov/pubmed/37072646
http://dx.doi.org/10.1002/advs.202204784