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Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1‐EEF1A1 Axis

Epigenetic dysregulation is reported in multiple cancers including Ewing sarcoma (EwS). However, the epigenetic networks underlying the maintenance of oncogenic signaling and therapeutic response remain unclear. Using a series of epigenetics‐ and complex‐focused CRISPR screens, RUVBL1, the ATPase co...

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Detalles Bibliográficos
Autores principales: Li, Mingli, Yang, Lu, Chan, Anthony K. N., Pokharel, Sheela Pangeni, Liu, Qiao, Mattson, Nicole, Xu, Xiaobao, Chang, Wen‐Han, Miyashita, Kazuya, Singh, Priyanka, Zhang, Leisi, Li, Maggie, Wu, Jun, Wang, Jinhui, Chen, Bryan, Chan, Lai N., Lee, Jaewoong, Zhang, Xu Hannah, Rosen, Steven T., Müschen, Markus, Qi, Jun, Chen, Jianjun, Hiom, Kevin, Bishop, Alexander J. R., Chen, Chun‐Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265057/
https://www.ncbi.nlm.nih.gov/pubmed/37075745
http://dx.doi.org/10.1002/advs.202206584