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Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1‐EEF1A1 Axis
Epigenetic dysregulation is reported in multiple cancers including Ewing sarcoma (EwS). However, the epigenetic networks underlying the maintenance of oncogenic signaling and therapeutic response remain unclear. Using a series of epigenetics‐ and complex‐focused CRISPR screens, RUVBL1, the ATPase co...
Autores principales: | Li, Mingli, Yang, Lu, Chan, Anthony K. N., Pokharel, Sheela Pangeni, Liu, Qiao, Mattson, Nicole, Xu, Xiaobao, Chang, Wen‐Han, Miyashita, Kazuya, Singh, Priyanka, Zhang, Leisi, Li, Maggie, Wu, Jun, Wang, Jinhui, Chen, Bryan, Chan, Lai N., Lee, Jaewoong, Zhang, Xu Hannah, Rosen, Steven T., Müschen, Markus, Qi, Jun, Chen, Jianjun, Hiom, Kevin, Bishop, Alexander J. R., Chen, Chun‐Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265057/ https://www.ncbi.nlm.nih.gov/pubmed/37075745 http://dx.doi.org/10.1002/advs.202206584 |
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