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Lymph Node Follicle‐Targeting STING Agonist Nanoshells Enable Single‐Shot M2e Vaccination for Broad and Durable Influenza Protection

The highly conserved matrix protein 2 ectodomain (M2e) of influenza viruses presents a compelling vaccine antigen candidate for stemming the pandemic threat of the mutation‐prone pathogen, yet the low immunogenicity of the diminutive M2e peptide renders vaccine development challenging. A highly pote...

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Detalles Bibliográficos
Autores principales: Tsai, Hsiao‐Han, Huang, Ping‐Han, Lin, Leon CW, Yao, Bing‐Yu, Liao, Wan‐Ting, Pai, Chen‐Hsueh, Liu, Yu‐Han, Chen, Hui‐Wen, Hu, Che‐Ming J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265066/
https://www.ncbi.nlm.nih.gov/pubmed/37092580
http://dx.doi.org/10.1002/advs.202206521