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High‐Performance Multi‐Dynamic Bond Cross‐Linked Hydrogel with Spatiotemporal siRNA Delivery for Gene–Cell Combination Therapy of Intervertebral Disc Degeneration

Chronic inflammatory diseases, such as intervertebral disc degeneration (IVDD), which affect the lives of hundreds of millions of people, still lack effective and precise treatments. In this study, a novel hydrogel system with many extraordinary properties is developed for gene–cell combination ther...

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Detalles Bibliográficos
Autores principales: Chen, Jiaxin, Zhu, Haifeng, Xia, Jiechao, Zhu, Yutao, Xia, Chen, Hu, Zehui, Jin, Yang, Wang, Ji, He, Yong, Dai, Jiayong, Hu, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265076/
https://www.ncbi.nlm.nih.gov/pubmed/37078785
http://dx.doi.org/10.1002/advs.202206306