Role of FLCN Phosphorylation in Insulin‐Mediated mTORC1 Activation and Tumorigenesis

The amino acid‐stimulated Rag GTPase pathway is one of the main pathways that regulate mechanistic target of rapamycin complex 1 (mTORC1) activation and function, but little is known about the effects of growth factors on Rag GTPase‐mediated mTORC1 activation. Here, a highly conserved insulin‐respon...

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Detalles Bibliográficos
Autores principales: Wang, Guoyan, Chen, Lei, Lei, Xinjian, Qin, Senlin, Geng, Huijun, Zheng, Yining, Xia, Chao, Yao, Junhu, Meng, Tong, Deng, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265093/
https://www.ncbi.nlm.nih.gov/pubmed/37083230
http://dx.doi.org/10.1002/advs.202206826