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Role of FLCN Phosphorylation in Insulin‐Mediated mTORC1 Activation and Tumorigenesis
The amino acid‐stimulated Rag GTPase pathway is one of the main pathways that regulate mechanistic target of rapamycin complex 1 (mTORC1) activation and function, but little is known about the effects of growth factors on Rag GTPase‐mediated mTORC1 activation. Here, a highly conserved insulin‐respon...
Autores principales: | Wang, Guoyan, Chen, Lei, Lei, Xinjian, Qin, Senlin, Geng, Huijun, Zheng, Yining, Xia, Chao, Yao, Junhu, Meng, Tong, Deng, Lu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265093/ https://www.ncbi.nlm.nih.gov/pubmed/37083230 http://dx.doi.org/10.1002/advs.202206826 |
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