CRISPR activation and interference as investigative tools in the cardiovascular system

CRISPR activation and interference (CRISPRa/i) technology offers the unprecedented possibility of achieving regulated gene expression both in vitro and in vivo. The DNA pairing specificity of a nuclease dead Cas9 (dCas9) is exploited to precisely target a transcriptional activator or repressor in pr...

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Detalles Bibliográficos
Autores principales: Carroll, Melissa S., Giacca, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265131/
https://www.ncbi.nlm.nih.gov/pubmed/36563996
http://dx.doi.org/10.1016/j.biocel.2022.106348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265131/
https://www.ncbi.nlm.nih.gov/pubmed/36563996
http://dx.doi.org/10.1016/j.biocel.2022.106348

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