A p21‐GFP zebrafish model of senescence for rapid testing of senolytics in vivo

Senescence drives the onset and severity of multiple ageing‐associated diseases and frailty. As a result, there has been an increased interest in mechanistic studies and in the search for compounds targeting senescent cells, known as senolytics. Mammalian models are commonly used to test senolytics...

Descripción completa

Detalles Bibliográficos
Autores principales: Morsli, Samir, Henriques, Catarina M., Ellis, Pamela S., Mortiboys, Heather, Baxendale, Sarah, Loynes, Catherine A., Renshaw, Stephen A., Bellantuono, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265157/
https://www.ncbi.nlm.nih.gov/pubmed/37039087
http://dx.doi.org/10.1111/acel.13835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265157/
https://www.ncbi.nlm.nih.gov/pubmed/37039087
http://dx.doi.org/10.1111/acel.13835

Ejemplares similares