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A p21‐GFP zebrafish model of senescence for rapid testing of senolytics in vivo
Senescence drives the onset and severity of multiple ageing‐associated diseases and frailty. As a result, there has been an increased interest in mechanistic studies and in the search for compounds targeting senescent cells, known as senolytics. Mammalian models are commonly used to test senolytics...
Autores principales: | Morsli, Samir, Henriques, Catarina M., Ellis, Pamela S., Mortiboys, Heather, Baxendale, Sarah, Loynes, Catherine A., Renshaw, Stephen A., Bellantuono, Ilaria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265157/ https://www.ncbi.nlm.nih.gov/pubmed/37039087 http://dx.doi.org/10.1111/acel.13835 |
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