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A p21‐GFP zebrafish model of senescence for rapid testing of senolytics in vivo

Senescence drives the onset and severity of multiple ageing‐associated diseases and frailty. As a result, there has been an increased interest in mechanistic studies and in the search for compounds targeting senescent cells, known as senolytics. Mammalian models are commonly used to test senolytics...

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Detalles Bibliográficos
Autores principales: Morsli, Samir, Henriques, Catarina M., Ellis, Pamela S., Mortiboys, Heather, Baxendale, Sarah, Loynes, Catherine A., Renshaw, Stephen A., Bellantuono, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265157/
https://www.ncbi.nlm.nih.gov/pubmed/37039087
http://dx.doi.org/10.1111/acel.13835

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