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Specific prediction of mortality by oxidative stress‐induced damage to RNA vs. DNA in humans

Modifications of nucleic acids (DNA and RNA) from oxidative stress is a potential driver of aging per se and of mortality in age‐associated medical disorders such as type 2 diabetes (T2D). In a human cohort, we found a strong prediction of all‐cause mortality by a marker of systemic oxidation of RNA...

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Detalles Bibliográficos
Autores principales: Jorgensen, Anders, Brandslund, Ivan, Ellervik, Christina, Henriksen, Trine, Weimann, Allan, Andersen, Per Kragh, Poulsen, Henrik E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265158/
https://www.ncbi.nlm.nih.gov/pubmed/37190886
http://dx.doi.org/10.1111/acel.13839