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Computational screen to identify potential targets for immunotherapeutic identification and removal of senescence cells

To prioritize gene and protein candidates that may enable the selective identification and removal of senescent cells, we compared gene expression signatures from replicative senescent cells to transcriptomics and proteomics atlases of normal human tissues and cell types. RNA‐seq samples from in vit...

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Detalles Bibliográficos
Autores principales: Deng, Eden Z., Fleishman, Reid H., Xie, Zhuorui, Marino, Giacomo B., Clarke, Daniel J. B., Ma'ayan, Avi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265163/
https://www.ncbi.nlm.nih.gov/pubmed/37082798
http://dx.doi.org/10.1111/acel.13809