The same heterozygous Col4A4 mutation triggered different renal pathological changes in Chinese family members

Background: Mutations in the collagen components of the glomerular basement membrane (GBM) often lead to hereditary glomerulonephritis. Previous studies have identified that autosomal dominant mutations of Col4A3, Col4A4 or Col4A5 are associated with thin basement membrane nephropathy (TBMN), Alport...

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Detalles Bibliográficos
Autores principales: Zhu, Fengming, Li, Yueqiang, Wang, Yuxi, Yao, Ying, Zeng, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265269/
https://www.ncbi.nlm.nih.gov/pubmed/37323683
http://dx.doi.org/10.3389/fgene.2023.1180149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265269/
https://www.ncbi.nlm.nih.gov/pubmed/37323683
http://dx.doi.org/10.3389/fgene.2023.1180149

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