Explore the dominant factor in prime editing via a view of DNA processing

Prime editing is a revolutionary gene-editing method that is capable of introducing insertions, deletions and base substitutions into the genome. However, the editing efficiency of Prime Editor (PE) is limited by the DNA repair process. Here, we show that overexpression of the flap structure-specifi...

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Detalles Bibliográficos
Autores principales: Xu, Zhimeng, Ma, Dacheng, Su, Houzhen, Jia, Xiaodong, Li, Yinqing, Lu, Yinying, Xie, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265487/
https://www.ncbi.nlm.nih.gov/pubmed/37325180
http://dx.doi.org/10.1016/j.synbio.2023.05.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265487/
https://www.ncbi.nlm.nih.gov/pubmed/37325180
http://dx.doi.org/10.1016/j.synbio.2023.05.007

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