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Starburst amacrine cells amplify optogenetic visual restoration through gap junctions

Ectopic induction of optogenetic actuators, such as channelrhodopsin, is a promising approach to restoring vision in the degenerating retina. However, the cell type-specific response of ectopic photoreception has not been well understood. There are limits to obtaining efficient gene expression in a...

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Detalles Bibliográficos
Autores principales: Katada, Yusaku, Kunimi, Hiromitsu, Serizawa, Naho, Lee, Deokho, Kobayashi, Kenta, Negishi, Kazuno, Okano, Hideyuki, Tanaka, Kenji F., Tsubota, Kazuo, Kurihara, Toshihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265492/
https://www.ncbi.nlm.nih.gov/pubmed/37324975
http://dx.doi.org/10.1016/j.omtm.2023.05.011