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A superoxide-driven redox state promotes geroconversion and resistance to senolysis in replication-stress associated senescence
Using S-phase synchronized RPE1-hTERT cells exposed to the DNA damaging agent, methyl methanesulfonate, we show the existence of a redox state associated with replication stress-induced senescence termed senescence-associated redox state (SA-redox state). SA-redox state is characterized by its react...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265521/ https://www.ncbi.nlm.nih.gov/pubmed/37285741 http://dx.doi.org/10.1016/j.redox.2023.102757 |