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The CH24H metabolite, 24HC, blocks viral entry by disrupting intracellular cholesterol homeostasis

Cholesterol-24-hydroxylase (CH24H or Cyp46a1) is a reticulum-associated membrane protein that plays an irreplaceable role in cholesterol metabolism in the brain and has been well-studied in several neuro-associated diseases in recent years. In the present study, we found that CH24H expression can be...

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Detalles Bibliográficos
Autores principales: Yuan, Yueming, Fang, An, Wang, Zongmei, Wang, Zhihui, Sui, Baokun, Zhu, Yunkai, Zhang, Yuan, Wang, Caiqian, Zhang, Rong, Zhou, Ming, Chen, Huanchun, Fu, Zhen F., Zhao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265526/
https://www.ncbi.nlm.nih.gov/pubmed/37285742
http://dx.doi.org/10.1016/j.redox.2023.102769